A Priliminary Note on the Pharmacological Study on Reserpine a New Alkaloid Isolated from Rauwolfia Serpentina
نویسندگان
چکیده
Rauwolfia serpentina, Benth, commonly known as Insanity herb has been used for a long time in Ayurvedic System of Indian Medicine. It has been highly advocated as a general sedative in sleeplessness, anxiety neurosia and hysteria and in the treatment of epilepsy, maniacal and acute insanity. Siddiqui & Siddiqui (19321935) studied the chemistry of some of the active principles extracted from the root of this
منابع مشابه
Effect of Growth Regulators and Culture Conditions on Direct Root Induction of Rauwolfia serpentina L. (Apocynaceae) Benth by Leaf Explants
Purpose: Rauwolfia serpentina (L.) Benth, from the family, Apocynaceae, is an important medicinal plant due to the alkaloid content of its root. The purpose of this study was to obtain roots directly from leaf explant using growth regulators. Methods: The leaf explant was inoculated on MS (Murashige and Skoog) medium supplemented with single and combinations of growth regulators. Root growth wa...
متن کاملHPTLC method validation of reserpine in Rauwolfia serpentina – A High Value medicinal Plant
Rauwolfia serpentina medicinal value well known in various system of medicine all over the world. Reserpine is an indole alkaloid and is important constituent of Rauwolfia which is reported to posses anti hypertensive and tranquilizing activity. In the present study High Performance Thin Layer Chromatography has been developed for quantification of Reserpine in Rauwolfia and its allied preparat...
متن کاملAction of reserpine-free extract of Rauwolfia serpentina on hypophysis-adrenocortical axis in rat.
(Abstract only) These results show that the alkaloid complex used here (Reserpine free alkaloids of Rauwolfia serpentina) modifies the response of the body to general stress. Thymus atrophy, adrenal enlargement and gastrointestinal ulcers have been described as the triad of ‘alarm reaction’ by SELYE who has also shown that adrenal enlargement due to stress occurs only in the presence of adenoph...
متن کاملMental depression in hypertensive patients treated for long periods with large doses of reserpine.
T HE introduction of Rauwolfia serpentina into this country by Wilkins and Judsonl and the purification of an active alkaloid, reserpine (Serpasil), has led to the widespread clinical IIS~ of the iatter drug not only in hypertension2,3 but also in neuropsychiatric conditions.” The purpose of this report is to describe the development of psychiatric complications in hypertensive patients treated...
متن کاملThe Use of Rauwolfia serpentina in Hypertensive Patients
The root of Sarpgandha is a species of flowering plant in the family Apocynaceae has been traditionally used in Ayurveda for many years to treat a variety of diseases that at first thought appear to bear little similarity to one another. These include insanity, epilepsy, insomnia, hysteria, eclampsia and hypertension. On reflection, however, these various diseases could have a common denominato...
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عنوان ژورنال:
دوره 89 شماره
صفحات -
تاریخ انتشار 1954